3hpt | pdb_00003hpt
From Proteopedia
Crystal structure of human FxA in complex with (S)-2-cyano-1-(2-methylbenzofuran-5-yl)-3-(2-oxo-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)azepan-3-yl)guanidine
Template:ABSTRACT PUBMED 19541481
About this Structure
3hpt is a 4 chain structure of Factor Xa with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Shi Y, Zhang J, Shi M, O'Connor SP, Bisaha SN, Li C, Sitkoff D, Pudzianowski AT, Chong S, Klei HE, Kish K, Yanchunas J Jr, Liu EC, Hartl KS, Seiler SM, Steinbacher TE, Schumacher WA, Atwal KS, Stein PD. Cyanoguanidine-based lactam derivatives as a novel class of orally bioavailable factor Xa inhibitors. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4034-41. Epub 2009 Jun 13. PMID:19541481 doi:10.1016/j.bmcl.2009.06.014
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Coagulation factor Xa
- Homo sapiens
- Ghosh, K.
- Kish, K.
- Klei, H E.
- Rushith, A.
- Blood clotting
- Blood coagulation
- Blood coagulation factor
- Cleavage on pair of basic residue
- Disulfide bond
- Egf-like domain
- Epidermal growth factor like domain
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydrolase
- Hydroxylation
- Protease
- Secreted
- Serine protease
- Zymogen
