3vhe | pdb_00003vhe

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File:3vhe.png

Template:STRUCTURE 3vhe

Crystal structure of human VEGFR2 kinase domain with a novel pyrrolopyrimidine inhibitor.

Template:ABSTRACT PUBMED 20833055

About this Structure

3vhe is a 1 chain structure of Vascular Endothelial Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Oguro Y, Miyamoto N, Okada K, Takagi T, Iwata H, Awazu Y, Miki H, Hori A, Kamiyama K, Imamura S. Design, synthesis, and evaluation of 5-methyl-4-phenoxy-5H-pyrrolo[3,2-d]pyrimidine derivatives: novel VEGFR2 kinase inhibitors binding to inactive kinase conformation. Bioorg Med Chem. 2010 Oct 15;18(20):7260-73. Epub 2010 Aug 13. PMID:20833055 doi:10.1016/j.bmc.2010.08.017

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OCA

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