3e51 | pdb_00003e51
From Proteopedia
Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor
About this Structure
3e51 is a 2 chain structure of RNA polymerase with sequence from Viruses. Full crystallographic information is available from OCA.
See Also
Reference
- Dragovich PS, Blazel JK, Ellis DA, Han Q, Kamran R, Kissinger CR, LeBrun LA, Li LS, Murphy DE, Noble M, Patel RA, Ruebsam F, Sergeeva MV, Shah AM, Showalter RE, Tran CV, Tsan M, Webber SE, Kirkovsky L, Zhou Y. Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda(6)-benzo[1',2',4']thiadiazin-3'-yl)- 5-hydroxy-2H-pyridazin-3-ones. Part 5: Exploration of pyridazinones containing 6-amino-substituents. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5635-9. Epub 2008 Aug 29. PMID:18796353 doi:10.1016/j.bmcl.2008.08.094
