2f3f | pdb_00002f3f

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File:2f3f.png

Template:STRUCTURE 2f3f

Crystal Structure of the Bace complex with BDF488, a macrocyclic inhibitor

Template:ABSTRACT PUBMED 16854060

About this Structure

2f3f is a 3 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Hanessian S, Yang G, Rondeau JM, Neumann U, Betschart C, Tintelnot-Blomley M. Structure-based design and synthesis of macroheterocyclic peptidomimetic inhibitors of the aspartic protease beta-site amyloid precursor protein cleaving enzyme (BACE). J Med Chem. 2006 Jul 27;49(15):4544-67. PMID:16854060 doi:10.1021/jm060154a

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