3fyk | pdb_00003fyk

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Template:STRUCTURE 3fyk

File:3fyk.png

Crystal structure of a benzthiophene lead bound to MAPKAP Kinase-2 (MK-2)

Template:ABSTRACT PUBMED 19616942

About this Structure

3fyk is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Anderson DR, Meyers MJ, Kurumbail RG, Caspers N, Poda GI, Long SA, Pierce BS, Mahoney MW, Mourey RJ, Parikh MD. Benzothiophene inhibitors of MK2. Part 2: improvements in kinase selectivity and cell potency. Bioorg Med Chem Lett. 2009 Aug 15;19(16):4882-4. Epub 2009 Feb 8. PMID:19616942 doi:10.1016/j.bmcl.2009.02.017

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