3klg
From Proteopedia
Crystal structure of AZT-resistant HIV-1 Reverse Transcriptase crosslinked to pre-translocation AZTMP-Terminated DNA (COMPLEX N)
Template:ABSTRACT PUBMED 20852643
About this Structure
3klg is a 8 chain structure of AZT-resistant HIV-1 reverse transcriptase and Reverse transcriptase with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
See Also
Reference
- Tu X, Das K, Han Q, Bauman JD, Clark AD Jr, Hou X, Frenkel YV, Gaffney BL, Jones RA, Boyer PL, Hughes SH, Sarafianos SG, Arnold E. Structural basis of HIV-1 resistance to AZT by excision. Nat Struct Mol Biol. 2010 Oct;17(10):1202-9. Epub 2010 Sep 19. PMID:20852643 doi:10.1038/nsmb.1908
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Human immunodeficiency virus 1
- Arnold, E.
- Sarafianos, S G.
- Tu, X.
- Aid
- Azt
- Azt excision
- Azt resistance
- Azt resistance mutation
- Dna polymerase
- Dna-directed dna polymerase
- Hiv
- Hiv-1
- Magnesium
- Metal-binding
- Multifunctional enzyme
- Myristate nuclease
- Nrti
- Nucleoside inhibitor
- Nucleotide excision
- P51/p66
- Resistance mechanism
- Reverse transcriptase
- Rna-directed dna polymerase
- Rt
- Transferase
- Transferase-dna complex
