3ika | pdb_00003ika
From Proteopedia
Crystal Structure of EGFR 696-1022 T790M Mutant Covalently Binding to WZ4002
Template:ABSTRACT PUBMED 20033049
About this Structure
3ika is a 2 chain structure of Epidermal Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Zhou W, Ercan D, Chen L, Yun CH, Li D, Capelletti M, Cortot AB, Chirieac L, Iacob RE, Padera R, Engen JR, Wong KK, Eck MJ, Gray NS, Janne PA. Novel mutant-selective EGFR kinase inhibitors against EGFR T790M. Nature. 2009 Dec 24;462(7276):1070-4. PMID:20033049 doi:10.1038/nature08622
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Receptor protein-tyrosine kinase
- Eck, M J.
- Yun, C H.
- Atp-binding
- Cell membrane
- Disease mutation
- Disulfide bond
- Egfr
- Glycoprotein
- Isopeptide bond
- Kinase
- Membrane
- Nucleotide-binding
- Phosphoprotein
- Receptor
- Secreted
- T790m
- Transferase
- Transmembrane
- Tumor suppressor
- Tyrosine-protein kinase
- Wz-4002
- Wz4002
