3jwc | pdb_00003jwc

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Template:STRUCTURE 3jwc

File:3jwc.png

Crystal structure of Bacillus anthracis (Y102F) dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-(3-(3,4,5-trimethoxyphenyl)prop-1-ynyl)-6-ethylpyrimidine (UCP120A)

Template:ABSTRACT PUBMED 020882962

About this Structure

3jwc is a 2 chain structure of Dihydrofolate reductase with sequence from Bacillus anthracis. Full crystallographic information is available from OCA.

See Also

Reference

  1. Beierlein JM, Karri NG, Anderson AC. Targeted mutations of Bacillus anthracis dihydrofolate reductase condense complex structure-activity relationships. J Med Chem. 2010 Oct 28;53(20):7327-36. PMID:20882962 doi:10.1021/jm100727t

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