2wvj | pdb_00002wvj

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File:2wvj.png

Template:STRUCTURE 2wvj

Mutation of Thr163 to Ser in Human Thymidine Kinase Shifts the Specificity from Thymidine towards the Nucleoside Analogue Azidothymidine

Template:ABSTRACT PUBMED 22385435

About this Structure

2wvj is a 8 chain structure of Thymidine kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Skovgaard T, Uhlin U, Munch-Petersen B. Comparative active-site mutation study of human and Caenorhabditis elegans thymidine kinase 1. FEBS J. 2012 May;279(10):1777-87. doi: 10.1111/j.1742-4658.2012.08554.x. Epub, 2012 Mar 21. PMID:22385435 doi:10.1111/j.1742-4658.2012.08554.x

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