3g90 | pdb_00003g90

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File:3g90.png

Template:STRUCTURE 3g90

JNK-3 bound to (Z)-5-fluoro-1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-3-(hydroxyimino)indolin-2-one

Template:ABSTRACT PUBMED 19361991

About this Structure

3g90 is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Cao J, Gao H, Bemis G, Salituro F, Ledeboer M, Harrington E, Wilke S, Taslimi P, Pazhanisamy S, Xie X, Jacobs M, Green J. Structure-based design and parallel synthesis of N-benzyl isatin oximes as JNK3 MAP kinase inhibitors. Bioorg Med Chem Lett. 2009 May 15;19(10):2891-5. Epub 2009 Mar 17. PMID:19361991 doi:10.1016/j.bmcl.2009.03.043

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