2zlf | pdb_00002zlf
From Proteopedia
The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase
About this Structure
2zlf is a 2 chain structure of Ribonucleotide reductase with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
See Also
Reference
- Xu H, Fairman JW, Wijerathna SR, Kreischer NR, LaMacchia J, Helmbrecht E, Cooperman BS, Dealwis C. The structural basis for peptidomimetic inhibition of eukaryotic ribonucleotide reductase: a conformationally flexible pharmacophore. J Med Chem. 2008 Aug 14;51(15):4653-9. Epub 2008 Jul 9. PMID:18610997 doi:10.1021/jm800350u
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Categories:
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- Ribonucleoside-diphosphate reductase
- Saccharomyces cerevisiae
- Cooperman, B S.
- Dealwis, C.
- Fairman, J W.
- Helmbrecht, E.
- Kreischer, N R.
- LaMacchia, J.
- Wijerathna, S R.
- Xu, H.
- Allosteric enzyme
- Atp-binding
- Dna replication
- Nucleotide-binding
- Oxidoreductase
- Peptidomimetic inhibition eukaryotic ribonucleotide reductase
- Phosphoprotein