3dl6 | pdb_00003dl6

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File:3dl6.png

Template:STRUCTURE 3dl6

Crystal Structure of the A287F/S290G Active Site Mutant of TS-DHFR from Cryptosporidium hominis

Template:ABSTRACT PUBMED 18672899

About this Structure

3dl6 is a 5 chain structure of Dihydrofolate reductase and Thymidylate synthase with sequence from Cryptosporidium hominis. Full crystallographic information is available from OCA.

See Also

Reference

  1. Martucci WE, Vargo MA, Anderson KS. Explaining an unusually fast parasitic enzyme: folate tail-binding residues dictate substrate positioning and catalysis in Cryptosporidium hominis thymidylate synthase. Biochemistry. 2008 Aug 26;47(34):8902-11. Epub 2008 Aug 2. PMID:18672899 doi:10.1021/bi800466z

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