3udd | pdb_00003udd

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Template:STRUCTURE 3udd

File:3udd.png

Tankyrase-1 in complex with small molecule inhibitor

Template:ABSTRACT PUBMED 22260203

About this Structure

3udd is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Shultz MD, Kirby CA, Stams T, Chin DN, Blank J, Charlat O, Cheng H, Cheung AK, Feng Y, Fortin PD, Hood T, Tyagi V, Xu M, Zhang B, Shao W. [1,2,4]Triazol-3-ylsulfanylmethyl)-3-phenyl-[1,2,4]oxadiazoles: Antagonists of the Wnt pathway that inhibit tankyrase 1&2 via novel adenosine pocket binding. J Med Chem. 2012 Jan 19. PMID:22260203 doi:10.1021/jm2011222

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