298d | pdb_0000298d

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Template:STRUCTURE 298d

File:298d.png

TARGETING THE MINOR GROOVE OF DNA: CRYSTAL STRUCTURES OF TWO COMPLEXES BETWEEN FURAN DERIVATIVES OF BERENIL AND THE DNA DODECAMER D(CGCGAATTCGCG)2

Template:ABSTRACT PUBMED 8917643

About this Structure

298d is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  1. Trent JO, Clark GR, Kumar A, Wilson WD, Boykin DW, Hall JE, Tidwell RR, Blagburn BL, Neidle S. Targeting the minor groove of DNA: crystal structures of two complexes between furan derivatives of berenil and the DNA dodecamer d(CGCGAATTCGCG)2. J Med Chem. 1996 Nov 8;39(23):4554-62. PMID:8917643 doi:10.1021/jm9604484
  2. Nguyen B, Neidle S, Wilson WD. A role for water molecules in DNA-ligand minor groove recognition. Acc Chem Res. 2009 Jan 20;42(1):11-21. PMID:18798655 doi:10.1021/ar800016q

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