4ac3 | pdb_00004ac3

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File:4ac3.png

Template:STRUCTURE 4ac3

S.pneumoniae GlmU in complex with an antibacterial inhibitor

Template:ABSTRACT PUBMED 22297115

About this Structure

4ac3 is a 1 chain structure with sequence from Streptococcus pneumoniae. Full crystallographic information is available from OCA.

Reference

  1. Green OM, McKenzie AR, Shapiro AB, Otterbein L, Ni H, Patten A, Stokes S, Albert R, Kawatkar S, Breed J. Inhibitors of acetyltransferase domain of N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetylt ransferase (GlmU). Part 1: Hit to lead evaluation of a novel arylsulfonamide series. Bioorg Med Chem Lett. 2012 Feb 15;22(4):1510-9. Epub 2012 Jan 14. PMID:22297115 doi:10.1016/j.bmcl.2012.01.016

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