3t70 | pdb_00003t70

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File:3t70.jpg

Template:STRUCTURE 3t70

5'-Diphenyl Nucleoside Inhibitors of Plasmodium falciparum dUTPase

Template:ABSTRACT PUBMED 22049550

About this Structure

3t70 is a 4 chain structure with sequence from Plasmodium falciparum. Full crystallographic information is available from OCA.

Reference

  1. Hampton SE, Baragana B, Schipani A, Bosch-Navarrete C, Musso-Buendia JA, Recio E, Kaiser M, Whittingham JL, Roberts SM, Shevtsov M, Brannigan JA, Kahnberg P, Brun R, Wilson KS, Gonzalez-Pacanowska D, Johansson NG, Gilbert IH. Design, synthesis, and evaluation of 5'-diphenyl nucleoside analogues as inhibitors of the Plasmodium falciparum dUTPase. ChemMedChem. 2011 Oct 4;6(10):1816-31. PMID:22049550

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