3utu | pdb_00003utu

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Template:ABSTRACT PUBMED 22907907

File:3utu.jpg


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3utu, resolution 1.55Å (default scene)
Ligands: 1TS, NA
Non-Standard Residues: TYS
Activity: Thrombin, with EC number 3.4.21.5
Related: 3dt0, 2zfo, 3eqo, 3f68, 3dux, 2ziq


Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



High affinity inhibitor of human thrombin

About this Structure

3utu is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Steinmetzer T, Baum B, Biela A, Klebe G, Nowak G, Bucha E. Beyond Heparinization: Design of Highly Potent Thrombin Inhibitors Suitable for Surface Coupling. ChemMedChem. 2012 Aug 20. doi: 10.1002/cmdc.201200292. PMID:22907907 doi:10.1002/cmdc.201200292

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