The Argonaute family of proteins is central to the RNA-induced silencing in eukaryotic organisms [1]. It was first found to be important for plant development and for germline stem-cell division in Drosophila Melanogaster, but further research revealed a much broader and essential role in protein synthesis, maintenance of genome integrity and RNA stability [2].
- ↑ Schirle NT, Macrae IJ. The Crystal Structure of Human Argonaute2. Science. 2012 Apr 26. PMID:22539551 doi:10.1126/science.1221551
- ↑ Hutvagner G, Simard MJ. Argonaute proteins: key players in RNA silencing. Nat Rev Mol Cell Biol. 2008 Jan;9(1):22-32. PMID:18073770 doi:10.1038/nrm2321
