2wip | pdb_00002wip
From Proteopedia
STRUCTURE OF CDK2-CYCLIN A COMPLEXED WITH 8-ANILINO-1-METHYL-4,5-DIHYDRO- 1H-PYRAZOLO[4,3-H] QUINAZOLINE-3-CARBOXYLIC ACID
Template:ABSTRACT PUBMED 19603809
About this Structure
2wip is a 4 chain structure of Cell Division Protein Kinase 2 and Cyclin. Full crystallographic information is available from OCA.
See Also
Reference
- Brasca MG, Amboldi N, Ballinari D, Cameron A, Casale E, Cervi G, Colombo M, Colotta F, Croci V, D'Alessio R, Fiorentini F, Isacchi A, Mercurio C, Moretti W, Panzeri A, Pastori W, Pevarello P, Quartieri F, Roletto F, Traquandi G, Vianello P, Vulpetti A, Ciomei M. Identification of N,1,4,4-Tetramethyl-8-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4,5-dihydr o-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide (PHA-848125), a Potent, Orally Available Cyclin Dependent Kinase Inhibitor. J Med Chem. 2009 Jul 15. PMID:19603809 doi:10.1021/jm9006559
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Categories:
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- Non-specific serine/threonine protein kinase
- Amboldi, N.
- Ballinari, D.
- Brasca, M G.
- Cameron, A D.
- Casale, E.
- Cervi, G.
- Ciomei, M.
- Colombo, M.
- Colotta, F.
- Croci, V.
- Dalessio, R.
- Fiorentini, F.
- Isacchi, A.
- Mercurio, C.
- Moretti, W.
- Panzeri, A.
- Pastori, W.
- Pevarello, P.
- Quartieri, F.
- Roletto, F.
- Traquandi, G.
- Vianello, P.
- Vulpetti, A.
- Atp-binding
- Cell cycle
- Cell division
- Cyclin
- Kinase
- Mitosis
- Nucleotide-binding
- Nucleus
- Phosphoprotein
- Phosphorylation
- Protein kinase
- Serine/threonine-protein 2 kinase
- Serine/threonine-protein kinase
- Transferase