3twj | pdb_00003twj

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File:3twj.png

Template:STRUCTURE 3twj

Rho-associated protein kinase 1 (ROCK 1) IN COMPLEX WITH RKI1447

Template:ABSTRACT PUBMED 22846914

About this Structure

3twj is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Patel RA, Forinash KD, Pireddu R, Sun Y, Sun N, Martin MP, Schonbrunn E, Lawrence NJ, Sebti SM. RKI-1447 is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and anti-tumor activities in breast cancer. Cancer Res. 2012 Jul 30. PMID:22846914 doi:10.1158/0008-5472.CAN-12-0954

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OCA

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