1sa4 | pdb_00001sa4
From Proteopedia
human protein farnesyltransferase complexed with FPP and R115777
Template:ABSTRACT PUBMED 15170324
About this Structure
1sa4 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Reid TS, Beese LS. Crystal structures of the anticancer clinical candidates R115777 (Tipifarnib) and BMS-214662 complexed with protein farnesyltransferase suggest a mechanism of FTI selectivity. Biochemistry. 2004 Jun 8;43(22):6877-84. PMID:15170324 doi:10.1021/bi049723b
