2vtp | pdb_00002vtp
From Proteopedia
IDENTIFICATION OF N-(4-PIPERIDINYL)-4-(2,6-DICHLOROBENZOYLAMINO)-1H-PYRAZOLE-3-CARBOXAMIDE (AT7519), A NOVEL CYCLIN DEPENDENT KINASE INHIBITOR USING FRAGMENT-BASED X-RAY CRYSTALLOGRAPHY AND STRUCTURE BASED DRUG DESIGN.
About this Structure
2vtp is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Wyatt PG, Woodhead AJ, Berdini V, Boulstridge JA, Carr MG, Cross DM, Davis DJ, Devine LA, Early TR, Feltell RE, Lewis EJ, McMenamin RL, Navarro EF, O'Brien MA, O'Reilly M, Reule M, Saxty G, Seavers LC, Smith DM, Squires MS, Trewartha G, Walker MT, Woolford AJ. Identification of N-(4-piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxamide (AT7519), a novel cyclin dependent kinase inhibitor using fragment-based X-ray crystallography and structure based drug design. J Med Chem. 2008 Aug 28;51(16):4986-99. Epub 2008 Jul 26. PMID:18656911 doi:10.1021/jm800382h
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Berdini, V.
- Boulstridge, J A.
- Brien, M A.O.
- Carr, M G.
- Cross, D M.
- Danillon, D.
- Davis, D J.
- Devine, L A.
- Early, T R.
- Feltell, R E.
- Lewis, E J.
- Mcmenamin, R L.
- Navarro, E F.
- Reilly, M O.
- Reule, M.
- Saxty, G.
- Seavers, L C.A.
- Smith, D.
- Squires, M S.
- Trewartha, G.
- Walker, M T.
- Woodhead, A J.
- Woolford, A J.
- Wyatt, P G.
- Cell cycle
- Mitosis
- Serine/threonine protein kinase
- Transferase
