1m17 | pdb_00001m17

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Template:STRUCTURE 1m17

File:1m17.png

Epidermal Growth Factor Receptor tyrosine kinase domain with 4-anilinoquinazoline inhibitor erlotinib

Template:ABSTRACT PUBMED 12196540

About this Structure

1m17 is a 1 chain structure with sequence from Homo sapiens. The June 2010 RCSB PDB Molecule of the Month feature on Epidermal Growth Factor Receptor by David Goodsell is 10.2210/rcsb_pdb/mom_2010_6. Full crystallographic information is available from OCA.

See Also

Reference

  1. Stamos J, Sliwkowski MX, Eigenbrot C. Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor. J Biol Chem. 2002 Nov 29;277(48):46265-72. Epub 2002 Aug 23. PMID:12196540 doi:10.1074/jbc.M207135200
  2. Lawson CL, Benoff B, Berger T, Berman HM, Carey J. E. coli trp repressor forms a domain-swapped array in aqueous alcohol. Structure. 2004 Jun;12(6):1099-108. PMID:15274929 doi:10.1016/j.str.2004.03.019

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