1y3g | pdb_00001y3g

Ligands:

3PL, CA, DMS, ZN

Non-Standard Residues:

AMM

Activity:

Thermolysin, with EC number 3.4.24.27

Structural annotation:
Resources:	CATH : 1Y3Ge02, 1Y3Ge01 InterPro : Ipr013832, Ipr006025, Ipr013856, Ipr011096, Ipr001570, Ipr005075 Pfam : PF01447, PF02868 UniProt : P00800

Functional annotation:
Cellular component:	extracellular region
Biological process:	proteolysis
Molecular function:	hydrolase activity metalloendopeptidase activity metal ion binding zinc ion binding calcium ion binding metallopeptidase activity peptidase activity

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, PDBsum, RCSB

Coordinates:

save as pdb, mmCIF, xml

About this Structure

1y3g is a 1 chain structure with sequence from Bacillus thermoproteolyticus. Full crystallographic information is available from OCA.

Juers DH, Kim J, Matthews BW, Sieburth SM. Structural analysis of silanediols as transition-state-analogue inhibitors of the benchmark metalloprotease thermolysin. Biochemistry. 2005 Dec 20;44(50):16524-8. PMID:16342943 doi:10.1021/bi051346v