2vdm | pdb_00002vdm

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Template:STRUCTURE 2vdm

File:2vdm.png

RE-REFINEMENT OF INTEGRIN ALPHAIIBBETA3 HEADPIECE BOUND TO ANTAGONIST TIROFIBAN

Template:ABSTRACT PUBMED 18710925

About this Structure

2vdm is a 4 chain structure with sequence from Homo sapiens and Mus musculus. This structure supersedes the now removed PDB entry 1ty5. Full crystallographic information is available from OCA.

See Also

Reference

  1. Springer TA, Zhu J, Xiao T. Structural basis for distinctive recognition of fibrinogen gammaC peptide by the platelet integrin alphaIIbbeta3. J Cell Biol. 2008 Aug 25;182(4):791-800. Epub 2008 Aug 18. PMID:18710925 doi:jcb.200801146
  2. Xiao T, Takagi J, Coller BS, Wang JH, Springer TA. Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics. Nature. 2004 Nov 4;432(7013):59-67. Epub 2004 Sep 19. PMID:15378069 doi:https://dx.doi.org/10.1038/nature02976

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