2fbr | pdb_00002fbr

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Template:STRUCTURE 2fbr

File:2fbr.png

Human transthyretin (TTR) complexed with bivalant amyloid inhibitor (4 carbon linker)

Template:ABSTRACT PUBMED 14583036

About this Structure

2fbr is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Green NS, Palaninathan SK, Sacchettini JC, Kelly JW. Synthesis and characterization of potent bivalent amyloidosis inhibitors that bind prior to transthyretin tetramerization. J Am Chem Soc. 2003 Nov 5;125(44):13404-14. PMID:14583036 doi:10.1021/ja030294z
  2. Choi S, Connelly S, Reixach N, Wilson IA, Kelly JW. Chemoselective small molecules that covalently modify one lysine in a non-enzyme protein in plasma. Nat Chem Biol. 2010 Feb;6(2):133-9. PMID:20081815 doi:10.1038/nchembio.281

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