1yy9 | pdb_00001yy9
From Proteopedia
Structure of the extracellular domain of the epidermal growth factor receptor in complex with the Fab fragment of cetuximab/Erbitux/IMC-C225
About this Structure
1yy9 is a 3 chain structure with sequence from Homo sapiens. The June 2010 RCSB PDB Molecule of the Month feature on Epidermal Growth Factor Receptor by David Goodsell is 10.2210/rcsb_pdb/mom_2010_6. Full crystallographic information is available from OCA.
See Also
Reference
- Li S, Schmitz KR, Jeffrey PD, Wiltzius JJ, Kussie P, Ferguson KM. Structural basis for inhibition of the epidermal growth factor receptor by cetuximab. Cancer Cell. 2005 Apr;7(4):301-11. PMID:15837620 doi:10.1016/j.ccr.2005.03.003
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Epidermal Growth Factor Receptor
- Homo sapiens
- RCSB PDB Molecule of the Month
- Receptor protein-tyrosine kinase
- Ferguson, K M.
- Jeffrey, P D.
- Kussie, P.
- Li, S.
- Schmitz, K R.
- Wiltzius, J J.W.
- Antigen:antibody complex
- Antitumor
- Cell surface receptor
- Drug
- Fab fragment
- Glycoprotein
- Immune system-transferase complex
- Tyrosine kinase
