3e37 | pdb_00003e37
From Proteopedia
Protein farnesyltransferase complexed with bisubstrate ethylenediamine scaffold inhibitor 5
About this Structure
3e37 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Hast MA, Fletcher S, Cummings CG, Pusateri EE, Blaskovich MA, Rivas K, Gelb MH, Van Voorhis WC, Sebti SM, Hamilton AD, Beese LS. Structural basis for binding and selectivity of antimalarial and anticancer ethylenediamine inhibitors to protein farnesyltransferase. Chem Biol. 2009 Feb 27;16(2):181-92. PMID:19246009 doi:10.1016/j.chembiol.2009.01.014