3pj8 | pdb_00003pj8

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File:3pj8.png

Template:STRUCTURE 3pj8

Structure of CDK2 in complex with a Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine.

Template:ABSTRACT PUBMED 21417417

About this Structure

3pj8 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Jorda R, Havlicek L, McNae IW, Walkinshaw MD, Voller J, Sturc A, Navratilova J, Kuzma M, Mistrik M, Bartek J, Strnad M, Krystof V. Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine: Evaluation of a Novel Selective Inhibitor of Cyclin-dependent Kinases with Antiproliferative Activity. J Med Chem. 2011 Mar 21. PMID:21417417 doi:10.1021/jm200064p

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