3ig6 | pdb_00003ig6
From Proteopedia
Low molecular weigth human Urokinase type Plasminogen activator 2-[6-(3'-Aminomethyl-biphenyl-3-yloxy)-4-(3-dimethylamino-pyrrolidin-1-yl)-3,5-difluoro-pyridin-2-yloxy]-4-dimethylamino-benzoic acid complex
Template:ABSTRACT PUBMED 19703768
About this Structure
3ig6 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- West CW, Adler M, Arnaiz D, Chen D, Chu K, Gualtieri G, Ho E, Huwe C, Light D, Phillips G, Pulk R, Sukovich D, Whitlow M, Yuan S, Bryant J. Identification of orally bioavailable, non-amidine inhibitors of Urokinase Plasminogen Activator (uPA). Bioorg Med Chem Lett. 2009 Oct 1;19(19):5712-5. Epub 2009 Aug 7. PMID:19703768 doi:10.1016/j.bmcl.2009.08.008
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- U-plasminogen activator
- Adler, M.
- Whitlow, M.
- Blood coagulation
- Disulfide bond
- Egf-like domain
- Fibrinolysis
- Glycoprotein
- Hydrolase
- Kringle
- Phosphoprotein
- Plasminogen activation
- Protease
- S1 site inhibitor
- Secreted
- Selective
- Serine protease
- Structure-based drug design
- Urokinase
- Zymogen
