2rd8 | pdb_00002rd8

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Template:STRUCTURE 2rd8

File:2rd8.png

Human Thymidylate Synthase Stabilized in Active Conformation by R163K Mutation: Asymmetry and Reactivity of Cys195

Template:ABSTRACT PUBMED 18370400

About this Structure

2rd8 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Gibson LM, Lovelace LL, Lebioda L. The R163K mutant of human thymidylate synthase is stabilized in an active conformation: structural asymmetry and reactivity of cysteine 195. Biochemistry. 2008 Apr 22;47(16):4636-43. Epub 2008 Mar 28. PMID:18370400 doi:10.1021/bi7019386

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