3kmc | pdb_00003kmc
From Proteopedia
Crystal structure of catalytic domain of TACE with tartrate-based inhibitor
Template:ABSTRACT PUBMED 20022498
About this Structure
3kmc is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Rosner KE, Guo Z, Orth P, Shipps GW Jr, Belanger DB, Chan TY, Curran PJ, Dai C, Deng Y, Girijavallabhan VM, Hong L, Lavey BJ, Lee JF, Li D, Liu Z, Popovici-Muller J, Ting PC, Vaccaro H, Wang L, Wang T, Yu W, Zhou G, Niu X, Sun J, Kozlowski JA, Lundell DJ, Madison V, McKittrick B, Piwinski JJ, Shih NY, Arshad Siddiqui M, Strickland CO. The discovery of novel tartrate-based TNF-alpha converting enzyme (TACE) inhibitors. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1189-93. Epub 2009 Dec 5. PMID:20022498 doi:10.1016/j.bmcl.2009.12.004
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- ADAM 17 endopeptidase
- Homo sapiens
- Orth, P.
- A disintegrin and metalloproteinase domain 17
- Cleavage on pair of basic residue
- Glycoprotein
- Hydrolase
- Membrane
- Metal-binding
- Metalloprotease
- Notch signaling pathway
- Phosphoprotein
- Protease
- Snake venom-like protease
- Tnf-alpha convertase
- Tnf-alpha-converting enzyme
- Zymogen
