1ikv | pdb_00001ikv

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Template:STRUCTURE 1ikv

File:1ikv.png

K103N Mutant HIV-1 Reverse Transcriptase in Complex with Efivarenz

Template:ABSTRACT PUBMED 11895437

About this Structure

1ikv is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

See Also

Reference

  1. Lindberg J, Sigurdsson S, Lowgren S, Andersson HO, Sahlberg C, Noreen R, Fridborg K, Zhang H, Unge T. Structural basis for the inhibitory efficacy of efavirenz (DMP-266), MSC194 and PNU142721 towards the HIV-1 RT K103N mutant. Eur J Biochem. 2002 Mar;269(6):1670-7. PMID:11895437
  2. Udier-Blagovic M, Tirado-Rives J, Jorgensen WL. Structural and energetic analyses of the effects of the K103N mutation of HIV-1 reverse transcriptase on efavirenz analogues. J Med Chem. 2004 Apr 22;47(9):2389-92. PMID:15084137 doi:10.1021/jm0303507

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