3inh | pdb_00003inh
From Proteopedia
Bace1 with the aminohydantoin Compound R-58
Template:ABSTRACT PUBMED 19968289
About this Structure
3inh is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Malamas MS, Erdei J, Gunawan I, Turner J, Hu Y, Wagner E, Fan K, Chopra R, Olland A, Bard J, Jacobsen S, Magolda RL, Pangalos M, Robichaud AJ. Design and synthesis of 5,5'-disubstituted aminohydantoins as potent and selective human beta-secretase (BACE1) inhibitors. J Med Chem. 2010 Feb 11;53(3):1146-58. PMID:19968289 doi:10.1021/jm901414e
