1tsr | pdb_00001tsr

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Template:STRUCTURE 1tsr

File:1tsr.png

P53 CORE DOMAIN IN COMPLEX WITH DNA

Template:ABSTRACT PUBMED 8023157

About this Structure

1tsr is a 5 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Cho Y, Gorina S, Jeffrey PD, Pavletich NP. Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations. Science. 1994 Jul 15;265(5170):346-55. PMID:8023157
  2. Martin AC, Facchiano AM, Cuff AL, Hernandez-Boussard T, Olivier M, Hainaut P, Thornton JM. Integrating mutation data and structural analysis of the TP53 tumor-suppressor protein. Hum Mutat. 2002 Feb;19(2):149-64. PMID:11793474 doi:10.1002/humu.10032
  3. Hicks JM, Hsu VL. The extended left-handed helix: a simple nucleic acid-binding motif. Proteins. 2004 May 1;55(2):330-8. PMID:15048824 doi:10.1002/prot.10630

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