3cs7 | pdb_00003cs7
From Proteopedia
FACTOR XA IN COMPLEX WITH THE INHIBITOR 1-(4-methoxyphenyl)-6-(4-(1-(pyrrolidin-1-ylmethyl)cyclopropyl)phenyl)-3-(trifluoromethyl)-5,6-dihydro-1H-pyrazolo[3,4-c]pyridin-7(4H)-one
About this Structure
3cs7 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Qiao JX, Cheney DL, Alexander RS, Smallwood AM, King SR, He K, Rendina AR, Luettgen JM, Knabb RM, Wexler RR, Lam PY. Achieving structural diversity using the perpendicular conformation of alpha-substituted phenylcyclopropanes to mimic the bioactive conformation of ortho-substituted biphenyl P4 moieties: discovery of novel, highly potent inhibitors of Factor Xa. Bioorg Med Chem Lett. 2008 Jul 15;18(14):4118-23. Epub 2008 May 29. PMID:18550370 doi:10.1016/j.bmcl.2008.05.095
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Coagulation factor Xa
- Homo sapiens
- Alexander, R S.
- Blood coagulation
- Blood coagulation factor
- Calcium-binding
- Cleavage on pair of basic residue
- Egf-like domain
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydrolase
- Hydroxylation
- Plasma
- Protease
- Protein inhibitor complex
- Serine protease
- Zymogen
