1tl3 | pdb_00001tl3

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Template:STRUCTURE 1tl3

File:1tl3.png

Crystal structure of hiv-1 reverse transcriptase in complex with gw450557

Template:ABSTRACT PUBMED 15537346

About this Structure

1tl3 is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

See Also

Reference

  1. Hopkins AL, Ren J, Milton J, Hazen RJ, Chan JH, Stuart DI, Stammers DK. Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1. J Med Chem. 2004 Nov 18;47(24):5912-22. PMID:15537346 doi:10.1021/jm040071z
  2. Weichsel A, Montfort WR, Ciesla J, Maley F. Promotion of purine nucleotide binding to thymidylate synthase by a potent folate analogue inhibitor, 1843U89. Proc Natl Acad Sci U S A. 1995 Apr 11;92(8):3493-7. PMID:7724588

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