1a4v | pdb_00001a4v

Ligands:

CA

Activity:

Lactose synthase, with EC number 2.4.1.22

Structural annotation:
Resources:	CATH : 1A4V000 InterPro : Ipr000545, Ipr001916 Pfam : PF00062 SCOP : d1a4v__ UniProt : P00709

Functional annotation:
Cellular component:	extracellular region extracellular space
Biological process:	signal transduction lactose biosynthetic process cell-cell signaling defense response to bacterium induction of apoptosis
Molecular function:	lactose synthase activity calcium ion binding

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, PDBsum, RCSB

Coordinates:

save as pdb, mmCIF, xml

About this Structure

1a4v is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Chandra N, Brew K, Acharya KR. Structural evidence for the presence of a secondary calcium binding site in human alpha-lactalbumin. Biochemistry. 1998 Apr 7;37(14):4767-72. PMID:9537992 doi:https://dx.doi.org/10.1021/bi973000t
Chaudhuri TK, Arai M, Terada TP, Ikura T, Kuwajima K. Equilibrium and kinetic studies on folding of the authentic and recombinant forms of human alpha-lactalbumin by circular dichroism spectroscopy. Biochemistry. 2000 Dec 19;39(50):15643-51. PMID:11112553