3hhm | pdb_00003hhm
From Proteopedia
Crystal structure of p110alpha H1047R mutant in complex with niSH2 of p85alpha and the drug wortmannin
About this Structure
3hhm is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Mandelker D, Gabelli SB, Schmidt-Kittler O, Zhu J, Cheong I, Huang CH, Kinzler KW, Vogelstein B, Amzel LM. A frequent kinase domain mutation that changes the interaction between PI3Kalpha and the membrane. Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):16996-7001. Epub 2009 Sep 23. PMID:19805105
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Phosphatidylinositol-4,5-bisphosphate 3-kinase
- Amzel, L M.
- Gabelli, S B.
- Mandelker, D.
- Vogelstein, B.
- 5-triphosphate
- Atp-binding
- Disease mutation
- H1047r
- Kinase
- Nucleotide-binding
- Oncogene
- P110
- P85
- Phosphatidilynositol 3
- Pi3k
- Pi3kca
- Pik3r1
- Transferase
- Transferase-oncoprotein complex
- Wortmannin
