1w3c | pdb_00001w3c

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Template:STRUCTURE 1w3c

File:1w3c.png

CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS3 PROTEASE IN COMPLEX WITH A PEPTIDOMIMETIC INHIBITOR

Template:ABSTRACT PUBMED 15588076

About this Structure

1w3c is a 4 chain structure with sequence from Viruses. Full crystallographic information is available from OCA.

See Also

Reference

  1. Ontoria JM, Di Marco S, Conte I, Di Francesco ME, Gardelli C, Koch U, Matassa VG, Poma M, Steinkuhler C, Volpari C, Harper S. The design and enzyme-bound crystal structure of indoline based peptidomimetic inhibitors of hepatitis C virus NS3 protease. J Med Chem. 2004 Dec 16;47(26):6443-6. PMID:15588076 doi:10.1021/jm049435d
  2. Di Marco S, Rizzi M, Volpari C, Walsh MA, Narjes F, Colarusso S, De Francesco R, Matassa VG, Sollazzo M. Inhibition of the hepatitis C virus NS3/4A protease. The crystal structures of two protease-inhibitor complexes. J Biol Chem. 2000 Mar 10;275(10):7152-7. PMID:10702283

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