1fkn | pdb_00001fkn

Non-Standard Residues:

1OL

Activity:

Memapsin 2, with EC number 3.4.23.46

Structural annotation:
Resources:	CATH : 1Fkna01, 1Fkna02, 1Fknb02, 1Fknb01 InterPro : Ipr009007, Ipr001461, Ipr009119, Ipr009120, Ipr001969 Pfam : PF00026 SCOP : d1fkna_, d1fknb_ UniProt : P56817

Evolutionary conservation:

Toggle Conservation Colors:

Rows = identical sequences:

Further Information:

Caveats,

Resources:

FirstGlance, OCA, PDBsum, RCSB

Coordinates:

save as pdb, mmCIF, xml

About this Structure

1fkn is a 4 chain structure with sequence from Homo sapiens. The July 2006 RCSB PDB Molecule of the Month feature on Amyloid-beta Precursor Protein by David S. Goodsell is 10.2210/rcsb_pdb/mom_2006_7. The July 2009 RCSB PDB Molecule of the Month feature on beta-Secretase by David Goodsell is 10.2210/rcsb_pdb/mom_2009_7. Full crystallographic information is available from OCA.

Hong L, Koelsch G, Lin X, Wu S, Terzyan S, Ghosh AK, Zhang XC, Tang J. Structure of the protease domain of memapsin 2 (beta-secretase) complexed with inhibitor. Science. 2000 Oct 6;290(5489):150-3. PMID:11021803