3l95 | pdb_00003l95
From Proteopedia
Crystal structure of the human Notch1 Negative Regulatory Region (NRR) bound to the fab fragment of an antagonist antibody
Template:ABSTRACT PUBMED 20393564
About this Structure
3l95 is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Wu Y, Cain-Hom C, Choy L, Hagenbeek TJ, de Leon GP, Chen Y, Finkle D, Venook R, Wu X, Ridgway J, Schahin-Reed D, Dow GJ, Shelton A, Stawicki S, Watts RJ, Zhang J, Choy R, Howard P, Kadyk L, Yan M, Zha J, Callahan CA, Hymowitz SG, Siebel CW. Therapeutic antibody targeting of individual Notch receptors. Nature. 2010 Apr 15;464(7291):1052-7. PMID:20393564 doi:10.1038/nature08878
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Hymowitz, S G.
- Leon, G P.de.
- Activator
- Alpha-beta-sandwich
- Ank repeat
- Antibody
- Cell cycle
- Cell membrane
- Developmental protein
- Differentiation
- Egf-like domain
- Fab fragment
- Glycoprotein
- Hd domain
- Immune system
- Lin12 notch cysteine-rich
- Lnr
- Membrane
- Metal-binding
- Notch signaling pathway
- Nrr
- Sea domain
- Signaling protein
