4dsf | pdb_00004dsf

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File:4dsf.png

Template:STRUCTURE 4dsf

Ternary complex of Bacillus DNA Polymerase I Large Fragment F710Y, DNA duplex, and rCTP (paired with dG of template) in presence of Mn2+

Template:ABSTRACT PUBMED 22648417

About this Structure

4dsf is a 6 chain structure with sequence from Geobacillus kaustophilus hta426. Full crystallographic information is available from OCA.

Reference

  1. Wang W, Wu EY, Hellinga HW, Beese LS. Structural factors that determine selectivity of a high-fidelity DNA polymerase for deoxy-, dideoxy-, and ribo-nucleotides. J Biol Chem. 2012 May 30. PMID:22648417 doi:10.1074/jbc.M112.366609
  2. Wang W, Hellinga HW, Beese LS. Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis. Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17644-8. Epub 2011 Oct 17. PMID:22006298 doi:10.1073/pnas.1114496108

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