1pl0 | pdb_00001pl0

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Template:STRUCTURE 1pl0

File:1pl0.png

Crystal structure of human ATIC in complex with folate-based inhibitor, BW2315U89UC

Template:ABSTRACT PUBMED 14966129

About this Structure

1pl0 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Cheong CG, Wolan DW, Greasley SE, Horton PA, Beardsley GP, Wilson IA. Crystal structures of human bifunctional enzyme aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase in complex with potent sulfonyl-containing antifolates. J Biol Chem. 2004 Apr 23;279(17):18034-45. Epub 2004 Feb 13. PMID:14966129 doi:10.1074/jbc.M313691200

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