1qbq | pdb_00001qbq

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Template:STRUCTURE 1qbq

File:1qbq.png

STRUCTURE OF RAT FARNESYL PROTEIN TRANSFERASE COMPLEXED WITH A CVIM PEPTIDE AND ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID.

Template:ABSTRACT PUBMED 9843427

About this Structure

1qbq is a 3 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  1. Strickland CL, Windsor WT, Syto R, Wang L, Bond R, Wu Z, Schwartz J, Le HV, Beese LS, Weber PC. Crystal structure of farnesyl protein transferase complexed with a CaaX peptide and farnesyl diphosphate analogue. Biochemistry. 1998 Nov 24;37(47):16601-11. PMID:9843427 doi:10.1021/bi981197z
  2. Cui G, Merz KM Jr. Computational studies of the farnesyltransferase ternary complex part II: the conformational activation of farnesyldiphosphate. Biochemistry. 2007 Oct 30;46(43):12375-81. Epub 2007 Oct 6. PMID:17918965 doi:10.1021/bi701324t

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