1y5v | pdb_00001y5v

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Template:STRUCTURE 1y5v

File:1y5v.png

tRNA-Guanine Transglycosylase (TGT) in complex with 6-Amino-4-(2-phenylethyl)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one

Template:ABSTRACT PUBMED 17524419

About this Structure

1y5v is a 1 chain structure with sequence from Zymomonas mobilis. Full crystallographic information is available from OCA.

Reference

  1. Stengl B, Meyer EA, Heine A, Brenk R, Diederich F, Klebe G. Crystal structures of tRNA-guanine transglycosylase (TGT) in complex with novel and potent inhibitors unravel pronounced induced-fit adaptations and suggest dimer formation upon substrate binding. J Mol Biol. 2007 Jul 13;370(3):492-511. Epub 2007 Apr 12. PMID:17524419 doi:10.1016/j.jmb.2007.04.008

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