2chm | pdb_00002chm
From Proteopedia
CRYSTAL STRUCTURE OF N2 SUBSTITUTED PYRAZOLO PYRIMIDINONES-A FLIPPED BINDING MODE IN PDE5
Template:ABSTRACT PUBMED 16759100
About this Structure
2chm is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Allerton CM, Barber CG, Beaumont KC, Brown DG, Cole SM, Ellis D, Lane CA, Maw GN, Mount NM, Rawson DJ, Robinson CM, Street SD, Summerhill NW. A novel series of potent and selective PDE5 inhibitors with potential for high and dose-independent oral bioavailability. J Med Chem. 2006 Jun 15;49(12):3581-94. PMID:16759100 doi:10.1021/jm060113e
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Allerton, C M.N.
- Barber, C G.
- Beaumont, K C.
- Brown, D G.
- Cole, S M.
- Ellis, D.
- Lane, C A.L.
- Maw, G N.
- Mount, N M.
- Rawson, D J.
- Robinson, C M.
- Street, S D.A.
- Summerhill, N W.
- Allosteric enzyme
- Camp
- Cgmp
- Cgmp-binding
- Chimera
- Hydrolase
- Inhibitor
- Magnesium
- Metal-binding
- Nucleotide-binding
- Phosphodiesterase 5
- Phosphorylation
