2itk | pdb_00002itk
From Proteopedia
human Pin1 bound to D-PEPTIDE
About this Structure
2itk is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Zhang Y, Daum S, Wildemann D, Zhou XZ, Verdecia MA, Bowman ME, Lucke C, Hunter T, Lu KP, Fischer G, Noel JP. Structural basis for high-affinity peptide inhibition of human Pin1. ACS Chem Biol. 2007 May 22;2(5):320-8. PMID:17518432 doi:https://dx.doi.org/10.1021/cb7000044
- Xu GG, Zhang Y, Mercedes-Camacho AY, Etzkorn FA. A reduced-amide inhibitor of Pin1 binds in a conformation resembling a twisted-amide transition state. Biochemistry. 2011 Nov 8;50(44):9545-50. Epub 2011 Oct 18. PMID:21980916 doi:10.1021/bi201055c
