2npu | pdb_00002npu

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Template:STRUCTURE 2npu

File:2npu.png

The solution structure of the rapamycin-binding domain of mTOR (FRB)

Template:ABSTRACT PUBMED 17684489

About this Structure

2npu is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  1. Veverka V, Crabbe T, Bird I, Lennie G, Muskett FW, Taylor RJ, Carr MD. Structural characterization of the interaction of mTOR with phosphatidic acid and a novel class of inhibitor: compelling evidence for a central role of the FRB domain in small molecule-mediated regulation of mTOR. Oncogene. 2008 Jan 24;27(5):585-95. Epub 2007 Aug 6. PMID:17684489

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OCA

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