2pin | pdb_00002pin
From Proteopedia
Thyroid receptor beta in complex with inhibitor
About this Structure
2pin is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Estebanez-Perpina E, Arnold LA, Jouravel N, Togashi M, Blethrow J, Mar E, Nguyen P, Phillips KJ, Baxter JD, Webb P, Guy RK, Fletterick RJ. Structural insight into the mode of action of a direct inhibitor of coregulator binding to the thyroid hormone receptor. Mol Endocrinol. 2007 Dec;21(12):2919-28. Epub 2007 Sep 6. PMID:17823305 doi:10.1210/me.2007-0174
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Baxter, J D.
- Estebanez-Perpina, E.
- Fletterick, R J.
- Guy, L R.
- Jouravel, N.
- Webb, P.
- Af-2 pocket
- Aromatic-beta-amino ketone
- Coregulator binding
- Hormone receptor
- Inhibitor
- Nuclear receptor
- Protein-protein interaction
- Structure-based drug design
- Surface interacting drug
- Thyroid receptor beta
